That is supported by results for withinrun coefficient of variation that is generally lower than 5% except for triglycerides, cholesterol, iga and igm and for betweenday coefficient of variation lower than 10% for all tested analytes table 2. For further instructions refer to the operators manual. Roche cobas 8000 modular analyzer series, continued intended use the cobas 8000 modular analyzer series is a fully automated system for indications for clinical chemistry analysis, intended for the in vitro qualitative and use quantitative determination of analytes in body fluids. Analytical performance evaluation of the cobas 6000. Certification concludes with calibration, qc and qa validation. Pdf clinical laboratories need to test patient samples precisely, accurately, and.
Psa in the specimen reacts with both the biotinylated monoclonal psaspecific antibody mouse and the. For more information about the cobas 6000, please visit roche diagnostics usa. Summary nutritional and macrocytic anemias can be caused by a deficiency of. The electrochemiluminescence immunoassay eclia is intended for useonelecsysandcobas e immunoassay analyzers. The performance evaluation of tinaquant roche cobas 6000 in. Their concern for patient care is paramount, and they. Core unit cobas c 501 module clinical chemistry analyzer cobas e 601 module immunoassay analyzer rack lines pc control unit the cobas 6000 analyzer series is a member of the cobas family of analyzers. This cobas 6000 system configurations consist of the following modules. Sodium, potassium, chloride ise cobas c501 gundersen. We recently started using roche cobas 6000 in our laboratory. Community forums for roche cobas 6000 relating to maintenance time for the cobas 6000 analyzer on medwrench.
An automated analyser is a medical laboratory instrument designed to measure different chemicals and other. The test is analyzed on a rochehitachi cobas 6000 chemistry analyzer. You will need alcohol prep pads, lint free gauze, and di water for the daily maintenance. A compact benchtop system for labs with limited floor space, this unit is designed to consolidate testing and increase efficiency while reducing total running costs of the laboratory. Contextsensitive means that wherever you are located within the cobas c 111 software, choosing help displays help text relating to that area of the software.
Cobas 6000 and adams showed higher hba1c value for uraemia and hyperbilir ubinaemia samples. Preface the cobas 6000 analyzer series is a fully automated, randomaccess, softwarecontrolled system for immunoassay and photometric analysis intended for qualitative and quantitative in vitro determinations using a wide variety of tests. The roche cobas 6000 and cobas 8000 are fully automated, softwarecontrolled systems for clinical chemistry and immunoassay analysis. Some of the information on this cd is available in pdfformat and requires. The cobas 8000 combines wellestablished analytical modules from roche modular analytics ise module. The cobas 6000 requires a continuous supply of purified water. The cobas 6000 analyzer series offers tailormade solutions for clinical chemistry and immunochemistry testing in medium workload laboratories. Hereby we present analytical validation with emphasis on method performance judgment for routine operation.
The instrument utilizes reusable optically pure plastic reaction cells that are changed on a monthly basis. Reflex testing is set up in the cobas to order a repeat of any very low result, to verify abnormal values. These measured properties of blood and other fluids may be useful in the diagnosis of disease. Validation of methods performance for routine biochemistry. An automated analyser is a medical laboratory instrument designed to measure different chemicals and other characteristics in a number of biological samples quickly, with minimal human assistance.
One configuration of the cobas 6000 analyzer series can contain up to two cobas c 501 modules. Daily investment in maintenance leads to greater than 99% uptime on your cobas 6000 analyzer. The roche cobas 6000 and cobas 8000 are fully automated, software controlled systems for clinical chemistry and immunoassay analysis. On board stability of reagents is up to 3 months and. Roche cobas 6000 c501 chemistry analyzer information. We evaluated the analytical performance of the cobas 6,000 analyzer roche diagnostics, which is considered a candidate for replacement of current hitachi 917 analyzers and for consolidation of chemistry and immunochemistry. E170 and cobas 6000 platforms cobas c 502, analytical unit identical to cobas c 501. Through our unrivalled investment in research and development. Table 1 site summary abbott site roche site site location canada netherlands annual clinical chemistry immunoassay tests 4. The clinical chemistry analyzer cobas c 311 5th generation of routine and dedicated chemistry experiences reagents one grip handling of reagents the unique concept of the cobas c packs allows for convenient reagent handling. On the c501 module the cobas 6000 utilizes spectrophotometric and ionspecific electrode measuring systems. All special wash programming necessary for avoiding carry. Jul 26, 2015 you will need alcohol prep pads, lint free gauze, and di water for the daily maintenance.
The system is a robust, high throughput and open floor model chemistry system boasting 92 assays with a maximum throughput of tests per hour. Cobas 6000 roche, germany is biochemistry analyzer for spectrophotometric, immunoturbidimetric and ionselective determination of biochemical analytes. How to do the daily maintenance on the cobas 6000 youtube. Follow these steps to ensure highquality test results. System design allows for easy system reconfiguration onsite to meet the. An ionselective electrode ise makes use of the unique properties of certain membrane materials to develop an electrical. It offers medium workload laboratories tailormade solutions for clinical chemistry. Roche, as global leader in diagnostics, is pioneering this shift in the healthcare landscape.
The cobas c reagent packs deliver maximum handling convenience with minimum reagent waste, liquid readytouse reagents and 90 day average onboard reagent stability. Process continues with assembly, repair, and diagnostics. They face constant pressure to lower operating costs while aspiring to grow their business in new areas. The cobas 6000 analyzer series combined the cobas c 501 analyzer for biochemical testing and the cobas e 601 analyzer for immunoassay into a single integrated system. Pdf cobas 8000 modular analyzer series evaluated under. Roche, as global leader in diagnostics, is pioneering this shift in the healthcare. Manufactured by roche diagnostics, cobas integra 400 plus is the perfect chemistry analyzer for laboratories with a throughput of 25,000 to 250,000 tests per year or 50 to 250 samples per day.
The cobas e reagent packs offer bestinclass handling convenience and reagent efficiences for. Roche cobas c501 chemistry analyzer diamond diagnostics. Cobas 6000 analyzer series modul c501 is stable analytical system for routine laboratory work. The cobas 6000 analyzer series is a member of the cobas modular platform. It is based upon the oxidation of oxalate by oxalate oxidase followed by measurement of hydrogen peroxide produced during the reaction by a peroxidasecatalyzed reaction. Fs ortho clinical diagnostics and unicel dxi 600 beckman coulter. Also, there is a daily pipe that should be run prior to restarting the instrument and the green rack. Device modification roche cobas 6000 series system, continued.
The automated immunoturbidimetry tinaquant roche cobas 6000 demonstrated acceptable precision, good recovery and is comparable with the hplc method. Flexible modularity offers individualized solutions to easily meet your challenging workflow needs. Photometry is the most common method for testing the amount of a specific analyte in a sample. Consolidation of analyzers is an emerging issue in clinical chemistry. The online help offers a quick and convenient way of finding. Clinical chemistry and immunoassay testing supporting the. Belonging to the cobas family of modular chemistry analyzers and a descendent to the roche modular p800 system, the roche cobas c601 is the chemistry module in the cobas 6000 modular system. Maintenance time for the cobas 6000 analyzer roche cobas. Device the control unit uses a graphical user interface to control all instrument description functions, and is comprised of a printer, tft monitor, keyboard and mouse continued and a personal computer using the windows xp operating system. The cobas 6000 correlates well with the reference system. Id 07 6865 0 rochehitachi cobas c 311, cobas c 501502 03555941 190 c. The principle of the ecl reaction is illustrated in.
By continuing to browse the site you are agreeing to our use of cookies. Roche cobas integra 400 plus the perfect analyzer for labs. Pdf cobas 6000 analyzer series host interface manual. Jun 06, 2016 daily investment in maintenance leads to greater than 99% uptime on your cobas 6000 analyzer. The nature of us switching to these analyzers involved us getting very little training in a very short time period, meaning most of us got less than 10 hours of training before we had to start using them long story. The cobas 6000 analyzer series is optimized for workloads using a combination of photometric and ionselective electrode determinations on the c501 module and electrochemiluminescence signal in the immunoassay analysis module, e601. Analyzers on which cobas c packs can be used 04489403 190 tina. When you speak of maintence, are you referring to the daily, weekly, or monthly. Roche cobas 6000 detailed product info pdf medwrench. Intended use the cobas 6000 series is a fully automated, randomaccess, software indications for controlled system for immunoassay and photometric analysis intended for use qualitative and quantitiative in vitro determinations using a wide variety of. It includes the necessary functionality to significantly improve laboratorys organization and increase workflow efficiency. Refurbishment includes disassembly and total restoration. The system used by the cobas 6000 is the millipore elix gulfstream clinical system 35c. Combined photometric and ise throughput up to 300 testshour.
The water is filtered from the reservoir through the inlet solenoid valve to the progard tl pretreatment pack. The cobas c111 instrument has a contextsensitive online help feature to aid in its operating. The performance evaluation of tinaquant roche cobas 6000. The roche elecsys total psa prostate specific antigen assay is a sandwich electrochemiluminescence immunoassay that employs a biotinylated monoclonal psaspecific antibody and a monoclonal psaspecific antibody labeled with ruthenium complex. Roche cobas 6000 routine operation gundersen health system. The most common mode used is id mode, which has provisions for processing samples that have damaged. Pac 3 x 1 ml code 589 10557897 122 precinorm protein 3 x 1 ml code 302 133127 122 precipath protein 3 x. This module performs over 110 measurements of proteins, enzymes, substrates and electrolytes, direct antiglobulin tests dats, and therapeutic drug monitoring tdms.
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